(2) OCCURRENCE OF MONOCLONAL GAMMOPATHY IN BALB/c MICE

Herpes Encephalitis in Monoclonal Gammopathy

Ninety percent of adult cases of encephalitis are caused by herpes simplex virus (HSV) type 1, and HSV type 2 encephalitis is clinically indistinguishable from HSV-1 encephalitis. There have been reports of HSV encephalitis in patients who have multiple myeloma and plasmacytoma,1-3 but this is the first case report describing HSV encephalitis in a patient with monoclonal gammopathy of unknown s...

Blood volume in monoclonal gammopathy.

The plasma volume, red cell volume, or both were measured in 170 normal, anemic, or polycythemic subjects. For anemic subjects without a serum protein abnormality or splenomegaly, the relationship between hematocrit and red cell volume was linear and predictable. In patients with a serum monoclonal globulin on electrophoresis, the plasma voluem was significantly increased for the hematocrit in ...

Monoclonal gammopathy of undetermined significance.

Monoclonal gammopathy of undetermined significance.

Monoclonal gammopathy of undetermined significance is not a benign condition. There is a significant increase in mortality associated with the risk of development of multiple myeloma and related disorders.

Monoclonal Gammopathy of Undetermined Significance

Monoclonal gammopathies are a heterogeneous group of disorders characterized by the stable or progressive proliferation of an abnormal clone of plasma cells that continue pro‐ ducing antibodies [4]. But because these immunoglobulin proteins are abnormal and mon‐ oclonal (identical copies of each other), these offer no protection against infections and can damage the kidney. This monoclonal immu...